Single-molecule mechanobiology

The Frank Zhang Lab at the Department of Biomedical Engineering, University of Massachusetts (UMass) Amherst, employs quantitative biophysical methods, including single-molecule detection techniques, to investigate the mechanobiology of the human circulatory system, tissue repair and regeneration, viral adhesion, and bioinspired soft materials.

Our three research areas involve:

Interfaces between biopolymers & circulatory flow

Mechanosensing & mechano-transduction in cells

Mechanobiology of intercellular interactions & viral entry

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